Effects of SMYD2‐mediated EML4‐ALK methylation on the signaling pathway and growth in non‐small‐cell lung cancer cells

A specific subtype of non‐small‐cell lung cancer (NSCLC) characterized with an EML4‐ALK fusion gene, which drives constitutive oncogenic activation of anaplastic lymphoma kinase (ALK), shows a good clinical response to ALK inhibitors. We have reported multiple examples implying the biological signif...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Wang, Rui, Deng, Xiaolan, Yoshioka, Yuichiro, Vougiouklakis, Theodore, Park, Jae‐Hyun, Suzuki, Takehiro, Dohmae, Naoshi, Ueda, Koji, Hamamoto, Ryuji, Nakamura, Yusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480063/
https://ncbi.nlm.nih.gov/pubmed/28370702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13245
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