Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway. MG e...

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發表在:Oxid Med Cell Longev
Main Authors: Hansen, Fernanda, Galland, Fabiana, Lirio, Franciane, de Souza, Daniela Fraga, Da Ré, Carollina, Pacheco, Rafaela Ferreira, Vizuete, Adriana Fernanda, Quincozes-Santos, André, Leite, Marina Concli, Gonçalves, Carlos-Alberto
格式: Artigo
語言:Inglês
出版: Hindawi 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480050/
https://ncbi.nlm.nih.gov/pubmed/28685011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9574201
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