Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats

BACKGROUND: Inflammatory responses in brain are primarily mediated by microglia, but growing evidence suggests a crucial importance of astrocytes. S100B, a calcium-binding protein secreted by astrocytes, has properties of a neurotrophic or an inflammatory cytokine. However, it is not known whether p...

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Hauptverfasser: Guerra, Maria Cristina, Tortorelli, Lucas S, Galland, Fabiana, Da Ré, Carollina, Negri, Elisa, Engelke, Douglas S, Rodrigues, Letícia, Leite, Marina C, Gonçalves, Carlos-Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198930/
https://ncbi.nlm.nih.gov/pubmed/21970823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-128
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