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Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway. MG e...

詳細記述

保存先:
書誌詳細
出版年:Oxid Med Cell Longev
主要な著者: Hansen, Fernanda, Galland, Fabiana, Lirio, Franciane, de Souza, Daniela Fraga, Da Ré, Carollina, Pacheco, Rafaela Ferreira, Vizuete, Adriana Fernanda, Quincozes-Santos, André, Leite, Marina Concli, Gonçalves, Carlos-Alberto
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480050/
https://ncbi.nlm.nih.gov/pubmed/28685011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9574201
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