Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage

The highly reactive dicarbonyl methylglyoxal (MGO) is mainly formed as byproduct of glycolysis. Therefore, high blood glucose levels determine increased MGO accumulation. Nonetheless, MGO levels are also increased as consequence of the ineffective action of its main detoxification pathway, the glyox...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Nigro, Cecilia, Leone, Alessia, Raciti, Gregory Alexander, Longo, Michele, Mirra, Paola, Formisano, Pietro, Beguinot, Francesco, Miele, Claudia
格式: Artigo
語言:Inglês
出版: MDPI 2017
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297820/
https://ncbi.nlm.nih.gov/pubmed/28106778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010188
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