Peroxisome Proliferator-activated Receptor-γ Activation Enhances Insulin-stimulated Glucose Disposal by Reducing ped/pea-15 Gene Expression in Skeletal Muscle Cells: EVIDENCE FOR INVOLVEMENT OF ACTIVATOR PROTEIN-1

The gene network responsible for inflammation-induced insulin resistance remains enigmatic. In this study, we show that, in L6 cells, rosiglitazone- as well as pioglitazone-dependent activation of peroxisome proliferator-activated receptor-γ (PPARγ) represses transcription of the ped/pea-15 gene, wh...

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Detalhes bibliográficos
Main Authors: Ungaro, Paola, Mirra, Paola, Oriente, Francesco, Nigro, Cecilia, Ciccarelli, Marco, Vastolo, Viviana, Longo, Michele, Perruolo, Giuseppe, Spinelli, Rosa, Formisano, Pietro, Miele, Claudia, Beguinot, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522290/
https://ncbi.nlm.nih.gov/pubmed/23105093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.406637
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