The Absence of p53 Promotes Metastasis in a Novel Somatic Mouse Model for Hepatocellular Carcinoma

We have generated a mouse model for hepatocellular carcinoma using somatic delivery of oncogene-bearing avian retroviral vectors to the liver cells of mice expressing the viral receptor TVA under the control of the albumin gene promoter (Alb-TVA mice). Viruses encoding mouse polyoma virus middle T a...

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Bibliografiske detaljer
Main Authors: Lewis, Brian C., Klimstra, David S., Socci, Nicholas D., Xu, Su, Koutcher, Jason A., Varmus, Harold E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC548003/
https://ncbi.nlm.nih.gov/pubmed/15684377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1228-1237.2005
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