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Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis

The gene encoding the receptor for hyaluronan-mediated motility (RHAMM) is overexpressed in many human cancers. However, it is unclear whether RHAMM plays a causal role in tumor initiation or progression. Using somatic gene transfer in a mouse model of islet cell tumorigenesis, we demonstrate that R...

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Main Authors: Du, Yi-Chieh Nancy, Chou, Chen-Kung, Klimstra, David S., Varmus, Harold
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189086/
https://ncbi.nlm.nih.gov/pubmed/21940500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114022108
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