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Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease

BACKGROUND & AIMS: N-linked glycosylation of proteins is critical for proper protein folding and trafficking to the plasma membrane. Drug transporters are one class of proteins that have reduced function when glycosylation is impaired. N-linked glycosylation of plasma proteins has also been inve...

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Bibliographic Details
Published in:Liver Int
Main Authors: Clarke, John D, Novak, Petr, Lake, April D, Hardwick, Rhiannon N, Cherrington, Nathan J
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479731/
https://ncbi.nlm.nih.gov/pubmed/28097795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13362
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