Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

Megakaryocytes are naturally polyploid cells that increase their ploidy by endomitosis. However, very little is known regarding the mechanism by which they escape the tetraploid checkpoint to become polyploid. Recently, it has been shown that the tetraploid checkpoint was regulated by the Hippo-p53...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Roy, Anita, Lordier, Larissa, Pioche-Durieu, Catherine, Souquere, Sylvie, Roy, Lydia, Rameau, Philippe, Lapierre, Valérie, Le Cam, Eric, Plo, Isabelle, Debili, Najet, Raslova, Hana, Vainchenker, William
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2016
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479626/
https://ncbi.nlm.nih.gov/pubmed/27515249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.149914
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires