P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis

TP53 also known as p53 is a tumor suppressor gene mutated in a variety of cancers. P53 is involved in cell cycle, apoptosis and DNA repair mechanisms and is thus tightly controlled by many regulators. Recently, strategies to treat cancer have focused on the development of MDM2 antagonists to induce...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Mahfoudhi, Emna, Lordier, Larissa, Marty, Caroline, Pan, Jiajia, Roy, Anita, Roy, Lydia, Rameau, Philippe, Abbes, Salem, Debili, Najet, Raslova, Hana, Chang, Yunhua, Debussche, Laurent, Vainchenker, William, Plo, Isabelle
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077990/
https://ncbi.nlm.nih.gov/pubmed/26959882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7881
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