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Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

Myelin is required for proper nervous system function. Schwann cells in developing nerves depend on extrinsic signals from the axon and from the extracellular matrix to first sort and ensheathe a single axon and then myelinate it. Neuregulin 1 type III (Nrg1III) and laminin α2β1γ1 (Lm211) are the ke...

詳細記述

保存先:
書誌詳細
出版年:PLoS Biol
主要な著者: Ghidinelli, Monica, Poitelon, Yannick, Shin, Yoon Kyoung, Ameroso, Dominique, Williamson, Courtney, Ferri, Cinzia, Pellegatta, Marta, Espino, Kevin, Mogha, Amit, Monk, Kelly, Podini, Paola, Taveggia, Carla, Nave, Klaus-Armin, Wrabetz, Lawrence, Park, Hwan Tae, Feltri, Maria Laura
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479503/
https://ncbi.nlm.nih.gov/pubmed/28636612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001408
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