Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

Myelin is required for proper nervous system function. Schwann cells in developing nerves depend on extrinsic signals from the axon and from the extracellular matrix to first sort and ensheathe a single axon and then myelinate it. Neuregulin 1 type III (Nrg1III) and laminin α2β1γ1 (Lm211) are the ke...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Ghidinelli, Monica, Poitelon, Yannick, Shin, Yoon Kyoung, Ameroso, Dominique, Williamson, Courtney, Ferri, Cinzia, Pellegatta, Marta, Espino, Kevin, Mogha, Amit, Monk, Kelly, Podini, Paola, Taveggia, Carla, Nave, Klaus-Armin, Wrabetz, Lawrence, Park, Hwan Tae, Feltri, Maria Laura
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479503/
https://ncbi.nlm.nih.gov/pubmed/28636612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001408
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