Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability

Hepatocellular carcinoma (HCC) remains one of the most difficult cancers to treat, with chemotherapies being relatively ineffective. Therefore, a better knowledge of molecular hepatocarcinogenesis will provide opportunities for designing targeted therapies. TPX2 (targeting protein for Xklp2) is over...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Hsu, Chao-Wen, Chen, Yu-Chia, Su, Hsing-Hao, Huang, Guan-Jin, Shu, Chih-Wen, Wu, Tony Tong-Lin, Pan, Hung-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479243/
https://ncbi.nlm.nih.gov/pubmed/28638452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17478
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