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Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2

Cell cycle deregulation is a common motif in human cancer, and multiple therapeutic strategies are aimed to prevent tumor cell proliferation. Whereas most current therapies are designed to arrest cell cycle progression either in G1/S or in mitosis, new proposals include targeting the intrinsic chrom...

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Detalhes bibliográficos
Main Authors: Pérez de Castro, Ignacio, Malumbres, Marcos
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636746/
https://ncbi.nlm.nih.gov/pubmed/23634259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912473306
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