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Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability

Hepatocellular carcinoma (HCC) remains one of the most difficult cancers to treat, with chemotherapies being relatively ineffective. Therefore, a better knowledge of molecular hepatocarcinogenesis will provide opportunities for designing targeted therapies. TPX2 (targeting protein for Xklp2) is over...

詳細記述

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書誌詳細
出版年:J Cancer
主要な著者: Hsu, Chao-Wen, Chen, Yu-Chia, Su, Hsing-Hao, Huang, Guan-Jin, Shu, Chih-Wen, Wu, Tony Tong-Lin, Pan, Hung-Wei
フォーマット: Artigo
言語:Inglês
出版事項: Ivyspring International Publisher 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479243/
https://ncbi.nlm.nih.gov/pubmed/28638452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17478
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