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Heterogeneous Tau-Tubulin Complexes Accelerate Microtubule Polymerization

Tau is an intrinsically disordered protein with a central role in the pathology of a number of neurodegenerative diseases. Tau normally functions to stabilize neuronal microtubules, although the mechanism underlying this function is not well understood. Of note is that the interaction between tau an...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Li, Xiao-Han, Rhoades, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479049/
https://ncbi.nlm.nih.gov/pubmed/28636913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.006
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