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Heterogeneous Tau-Tubulin Complexes Accelerate Microtubule Polymerization

Tau is an intrinsically disordered protein with a central role in the pathology of a number of neurodegenerative diseases. Tau normally functions to stabilize neuronal microtubules, although the mechanism underlying this function is not well understood. Of note is that the interaction between tau an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Li, Xiao-Han, Rhoades, Elizabeth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479049/
https://ncbi.nlm.nih.gov/pubmed/28636913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.006
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