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Tau Binds to Multiple Tubulin Dimers with Helical Structure

Understanding the mechanism by which tau binds to and promotes microtubule (MT) assembly as part of its native function may also provide insight into its loss of function that occurs in neurodegenerative disease. Both mechanistic and structural studies of tau have been hindered by its intrinsic diso...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Chem Soc
Egile Nagusiak: Li, Xiao-Han, Culver, Jacob A., Rhoades, Elizabeth
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697934/
https://ncbi.nlm.nih.gov/pubmed/26165802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04561
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