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Tau Binds to Multiple Tubulin Dimers with Helical Structure
Understanding the mechanism by which tau binds to and promotes microtubule (MT) assembly as part of its native function may also provide insight into its loss of function that occurs in neurodegenerative disease. Both mechanistic and structural studies of tau have been hindered by its intrinsic diso...
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| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697934/ https://ncbi.nlm.nih.gov/pubmed/26165802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04561 |
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