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Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis

NAD and its reduced form NADH function as essential redox cofactors and have major roles in determining cellular metabolic features. NAD can be synthesized through the deamidated and amidated pathways, for which the key reaction involves adenylylation of nicotinic acid mononucleotide (NaMN) and nico...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Main Authors: Wang, Xueying, Zhou, Yongjin J., Wang, Lei, Liu, Wujun, Liu, Yuxue, Peng, Chang, Zhao, Zongbao K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478990/
https://ncbi.nlm.nih.gov/pubmed/28455340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00692-17
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