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Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis

NAD and its reduced form NADH function as essential redox cofactors and have major roles in determining cellular metabolic features. NAD can be synthesized through the deamidated and amidated pathways, for which the key reaction involves adenylylation of nicotinic acid mononucleotide (NaMN) and nico...

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書誌詳細
出版年:Appl Environ Microbiol
主要な著者: Wang, Xueying, Zhou, Yongjin J., Wang, Lei, Liu, Wujun, Liu, Yuxue, Peng, Chang, Zhao, Zongbao K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478990/
https://ncbi.nlm.nih.gov/pubmed/28455340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00692-17
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