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Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis

NAD and its reduced form NADH function as essential redox cofactors and have major roles in determining cellular metabolic features. NAD can be synthesized through the deamidated and amidated pathways, for which the key reaction involves adenylylation of nicotinic acid mononucleotide (NaMN) and nico...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Wang, Xueying, Zhou, Yongjin J., Wang, Lei, Liu, Wujun, Liu, Yuxue, Peng, Chang, Zhao, Zongbao K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478990/
https://ncbi.nlm.nih.gov/pubmed/28455340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00692-17
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