Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo

Runx transcription factors comprise a family of proteins that are essential for organogenesis. A unique nuclear matrix-targeting signal in the C terminus directs these factors to their appropriate subnuclear domains. At these sites, they interact with coregulatory proteins and target genes. We have...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Javed, Amjad, Barnes, George L., Pratap, Jitesh, Antkowiak, Tomasz, Gerstenfeld, Louis C., van Wijnen, Andre J., Stein, Janet L., Lian, Jane B., Stein, Gary S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC547873/
https://ncbi.nlm.nih.gov/pubmed/15665096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409121102
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi