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A Dynamical Model for Activating and Silencing the Mitotic Checkpoint
The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism, exclusively sensitive to the states of kinetochores attached to microtubules. During metaphase, the anaphase-promoting complex/cyclosome (APC/C) is inhibited by the SAC but it rapidly switches to its active form followin...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478649/ https://ncbi.nlm.nih.gov/pubmed/28634351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04218-2 |
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