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In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint

BACKGROUND: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct segregation of chromosomes by restraining cell cycle progression from entering anaphase until all chromosomes have made proper bipolar attachments to the mitotic spindle. Its...

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Detalles Bibliográficos
Main Authors: Ibrahim, Bashar, Diekmann, Stephan, Schmitt, Eberhard, Dittrich, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215771/
https://ncbi.nlm.nih.gov/pubmed/18253502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001555
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