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In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint

BACKGROUND: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct segregation of chromosomes by restraining cell cycle progression from entering anaphase until all chromosomes have made proper bipolar attachments to the mitotic spindle. Its...

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Autors principals: Ibrahim, Bashar, Diekmann, Stephan, Schmitt, Eberhard, Dittrich, Peter
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215771/
https://ncbi.nlm.nih.gov/pubmed/18253502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001555
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