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In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint

BACKGROUND: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct segregation of chromosomes by restraining cell cycle progression from entering anaphase until all chromosomes have made proper bipolar attachments to the mitotic spindle. Its...

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Détails bibliographiques
Auteurs principaux: Ibrahim, Bashar, Diekmann, Stephan, Schmitt, Eberhard, Dittrich, Peter
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215771/
https://ncbi.nlm.nih.gov/pubmed/18253502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001555
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