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A Dynamical Model for Activating and Silencing the Mitotic Checkpoint

The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism, exclusively sensitive to the states of kinetochores attached to microtubules. During metaphase, the anaphase-promoting complex/cyclosome (APC/C) is inhibited by the SAC but it rapidly switches to its active form followin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Henze, Richard, Dittrich, Peter, Ibrahim, Bashar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478649/
https://ncbi.nlm.nih.gov/pubmed/28634351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04218-2
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