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A Dynamical Model for Activating and Silencing the Mitotic Checkpoint

The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism, exclusively sensitive to the states of kinetochores attached to microtubules. During metaphase, the anaphase-promoting complex/cyclosome (APC/C) is inhibited by the SAC but it rapidly switches to its active form followin...

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Publicado en:Sci Rep
Autores principales: Henze, Richard, Dittrich, Peter, Ibrahim, Bashar
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478649/
https://ncbi.nlm.nih.gov/pubmed/28634351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04218-2
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