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Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37

Tannerella forsythia is a periodontal pathogen expressing six secretory proteolytic enzymes with a unique multidomain structure referred to as KLIKK proteases. Two of these proteases, karilysin and mirolysin, were previously shown to protect the bacterium against complement-mediated bactericidal act...

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Detalhes bibliográficos
Publicado no:Biol Chem
Main Authors: Koneru, Lahari, Ksiazek, Miroslaw, Waligorska, Irena, Straczek, Anna, Lukasik, Magdalena, Madej, Mariusz, Thøgersen, Ida B., Enghild, Jan J., Potempa, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478484/
https://ncbi.nlm.nih.gov/pubmed/27997347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2016-0267
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