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Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37

Tannerella forsythia is a periodontal pathogen expressing six secretory proteolytic enzymes with a unique multidomain structure referred to as KLIKK proteases. Two of these proteases, karilysin and mirolysin, were previously shown to protect the bacterium against complement-mediated bactericidal act...

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Dettagli Bibliografici
Pubblicato in:Biol Chem
Autori principali: Koneru, Lahari, Ksiazek, Miroslaw, Waligorska, Irena, Straczek, Anna, Lukasik, Magdalena, Madej, Mariusz, Thøgersen, Ida B., Enghild, Jan J., Potempa, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478484/
https://ncbi.nlm.nih.gov/pubmed/27997347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2016-0267
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