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Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop

All prokaryotic genes encoding putative serpins identified to date are found in environmental and commensal microorganisms, and only very few prokaryotic serpins have been investigated from a mechanistic standpoint. Herein, we characterized a novel serpin (miropin) from the human pathogen Tannerella...

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Pubblicato in:J Biol Chem
Autori principali: Ksiazek, Miroslaw, Mizgalska, Danuta, Enghild, Jan J., Scavenius, Carsten, Thogersen, Ida B., Potempa, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281766/
https://ncbi.nlm.nih.gov/pubmed/25389290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601716
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