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Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop

All prokaryotic genes encoding putative serpins identified to date are found in environmental and commensal microorganisms, and only very few prokaryotic serpins have been investigated from a mechanistic standpoint. Herein, we characterized a novel serpin (miropin) from the human pathogen Tannerella...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ksiazek, Miroslaw, Mizgalska, Danuta, Enghild, Jan J., Scavenius, Carsten, Thogersen, Ida B., Potempa, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281766/
https://ncbi.nlm.nih.gov/pubmed/25389290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601716
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