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A metalloproteinase mirolysin of Tannerella forsythia inhibits all pathways of the complement system

Recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. In particular, bacteria-mediated cleavage of C5 and subsequent rel...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Jusko, Monika, Potempa, Jan, Mizgalska, Danuta, Bielecka, Ewa, Ksiazek, Miroslaw, Riesbeck, Kristian, Garred, Peter, Eick, Sigrun, Blom, Anna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546851/
https://ncbi.nlm.nih.gov/pubmed/26209620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402892
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