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A metalloproteinase mirolysin of Tannerella forsythia inhibits all pathways of the complement system

Recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. In particular, bacteria-mediated cleavage of C5 and subsequent rel...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jusko, Monika, Potempa, Jan, Mizgalska, Danuta, Bielecka, Ewa, Ksiazek, Miroslaw, Riesbeck, Kristian, Garred, Peter, Eick, Sigrun, Blom, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546851/
https://ncbi.nlm.nih.gov/pubmed/26209620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402892
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