Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage

Spermidine, a natural polyamine presented widely in mammalian cells, has been implicated to extend the lifespan of several model organisms by inducing autophagy. However, the effect of spermidine against neuronal damage has not yet been fully determined. In this study, neuronal cell injury was induc...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Yang, Yi, Chen, Sicong, Zhang, Yuqing, Lin, Xiaoxia, Song, Yiyin, Xue, Zhaoliang, Qian, Haoran, Wang, Shanshan, Wan, Guihua, Zheng, Xiaoxiang, Zhang, Lihui
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477584/
https://ncbi.nlm.nih.gov/pubmed/28383560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.161
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