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RNase L Cleavage Products Promote Switch from Autophagy to Apoptosis by Caspase-Mediated Cleavage of Beclin-1

Autophagy and apoptosis share regulatory molecules enabling crosstalk in pathways that affect cellular homeostasis including response to viral infections and survival of tumor cells. Ribonuclease L (RNase L) is an antiviral endonuclease that is activated in virus-infected cells and cleaves viral and...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Siddiqui, Mohammad Adnan, Mukherjee, Sushovita, Manivannan, Praveen, Malathi, Krishnamurthy
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581211/
https://ncbi.nlm.nih.gov/pubmed/26263979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160817611
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