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VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
Vacuolar protein sorting-associated protein 35 (VPS35) is involved in retrograde transport of proteins from endosomes to trans-Golgi network. Gene mutations in VPS35 are linked to autosomal dominant late-onset Parkinson's disease (PD). Although the identification of VPS35 mutations has provided...
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| Опубликовано в: : | Cell Death Dis |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477581/ https://ncbi.nlm.nih.gov/pubmed/28383562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.157 |
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