Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model

Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. Here we performed a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ham, Sangwoo, Lee, Yun-Il, Jo, Minkyung, Kim, Hyojung, Kang, Hojin, Jo, Areum, Lee, Gum Hwa, Mo, Yun Jeong, Park, Sang Chul, Lee, Yun Song, Shin, Joo-Ho, Lee, Yunjong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428870/
https://ncbi.nlm.nih.gov/pubmed/28366931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00614-w
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