An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

The activity of the human immunodeficiency virus (HIV) protease is essential for processing of the gag-pol precursor proteins and maturation of infectious virions. We have prepared a peptidomimetic inhibitor, U-75875, that inhibited HIV-1 gag-pol protein processing in an essentially irreversible man...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ashorn, P, McQuade, T J, Thaisrivongs, S, Tomasselli, A G, Tarpley, W G, Moss, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC54769/
https://ncbi.nlm.nih.gov/pubmed/2217178
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk