Effects of U-75875, a peptidomimetic inhibitor of retroviral proteases, on simian immunodeficiency virus infection in rhesus monkeys.

U-75875 inhibits human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus (SIV) proteases and blocks Gag-Pol protein processing and viral maturation and replication in vitro. Rhesus monkeys were treated with vehicle alone or with formulated U-75875 at doses of 7 or 20 mg/kg of bo...

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Hlavní autoři: Martin, L N, Soike, K F, Murphey-Corb, M, Bohm, R P, Roberts, E D, Kakuk, T J, Thaisrivongs, S, Vidmar, T J, Ruwart, M J, Davio, S R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC188198/
https://ncbi.nlm.nih.gov/pubmed/7522427
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