An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

The activity of the human immunodeficiency virus (HIV) protease is essential for processing of the gag-pol precursor proteins and maturation of infectious virions. We have prepared a peptidomimetic inhibitor, U-75875, that inhibited HIV-1 gag-pol protein processing in an essentially irreversible man...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ashorn, P, McQuade, T J, Thaisrivongs, S, Tomasselli, A G, Tarpley, W G, Moss, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7472
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!