Preliminary study of a novel transfection modality for in vivo siRNA delivery to vocal fold fibroblasts

OBJECTIVE: An obstacle to clinical use of RNA-based gene suppression is instability and inefficiency of current delivery modalities. Nanoparticle delivery likely holds great promise, but the kinetics and transfection conditions must be optimized prior to in vivo utility. We investigated a RNA nanopa...

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Bibliografske podrobnosti
izdano v:Laryngoscope
Main Authors: Kraja, Iv, Bing, Renjie, Hiwatashi, Nao, Rousseau, Bernard, Nalband, Danielle, Kirshenbaum, Kent, Branski, Ryan C.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476483/
https://ncbi.nlm.nih.gov/pubmed/27996099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.26432
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