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Nanoparticle delivery of RNA-based therapeutics to alter the vocal fold tissue response to injury

OBJECTIVE(S): Our laboratory and others hypothesize Smad3 is a principle mediator of the fibrotic phenotype in the vocal folds (VF), and we further posit that alteration of Smad3 expression through short interfering (si)RNA holds therapeutic promise, yet delivery remains challenging. To address this...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Laryngoscope
Egile Nagusiak: Hiwatashi, Nao, Kraja, Iv, Benedict, Peter A., Dion, Gregory R., Bing, Renjie, Rousseau, Bernard, Amin, Milan R., Nalband, Danielle M., Kirshenbaum, Kent, Branski, Ryan C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910268/
https://ncbi.nlm.nih.gov/pubmed/29238989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.27047
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