Preliminary study of a novel transfection modality for in vivo siRNA delivery to vocal fold fibroblasts

OBJECTIVE: An obstacle to clinical use of RNA-based gene suppression is instability and inefficiency of current delivery modalities. Nanoparticle delivery likely holds great promise, but the kinetics and transfection conditions must be optimized prior to in vivo utility. We investigated a RNA nanopa...

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Bibliografiske detaljer
Udgivet i:Laryngoscope
Main Authors: Kraja, Iv, Bing, Renjie, Hiwatashi, Nao, Rousseau, Bernard, Nalband, Danielle, Kirshenbaum, Kent, Branski, Ryan C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476483/
https://ncbi.nlm.nih.gov/pubmed/27996099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.26432
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