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ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction
Estrogen-related receptor α (ERRα) is a member of the nuclear receptor superfamily controlling energy homeostasis; however, its precise role in regulating antiviral innate immunity remains to be clarified. Here, we showed that ERRα deficiency conferred resistance to viral infection both in vivo and...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476288/ https://ncbi.nlm.nih.gov/pubmed/28591144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006347 |
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