ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction

Estrogen-related receptor α (ERRα) is a member of the nuclear receptor superfamily controlling energy homeostasis; however, its precise role in regulating antiviral innate immunity remains to be clarified. Here, we showed that ERRα deficiency conferred resistance to viral infection both in vivo and...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: He, Xiang, Ma, Shengli, Tian, Yinyin, Wei, Congwen, Zhu, Yongjie, Li, Feng, Zhang, Pingping, Wang, Penghao, Zhang, Yanhong, Zhong, Hui
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476288/
https://ncbi.nlm.nih.gov/pubmed/28591144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006347
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