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Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β
The double-stranded RNA mimetic poly(I:C) and lipopolysaccharide (LPS) activate Toll-like receptors 3 (TLR3) and TLR4, respectively, triggering the activation of TANK (TRAF family member-associated NF-κB activator)-binding kinase 1 (TBK1) complexes, the phosphorylation of interferon regulatory facto...
Guardat en:
| Publicat a: | Biochem J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350611/ https://ncbi.nlm.nih.gov/pubmed/28159912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160992 |
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