cGAS-STING-TBK1-IRF3/7 induced interferon-β contributes to the clearing of non tuberculous mycobacterial infection in mice

Type I interferons (IFN-I), such as IFN-α and IFN-β are important messengers in the host response against bacterial infections. Knowledge about the role of IFN-I in infections by nontuberculous mycobacteria (NTM) is limited. Here we show that macrophages infected with pathogens of the Mycobacterium...

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Bibliographic Details
Published in:Virulence
Main Authors: Ruangkiattikul, Nanthapon, Nerlich, Andreas, Abdissa, Ketema, Lienenklaus, Stefan, Suwandi, Abdulhadi, Janze, Nina, Laarmann, Kristin, Spanier, Julia, Kalinke, Ulrich, Weiss, Siegfried, Goethe, Ralph
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711412/
https://ncbi.nlm.nih.gov/pubmed/28422568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1321191
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