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Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels.

Secretory proteins expressed in Chinese hamster ovary (CHO) cells interact to various degrees with glucose-regulated protein 78 (GRP78), a resident protein of the endoplasmic reticulum. von Willebrand factor (vWF) and wild-type tissue plasminogen activator (tPA) are efficiently secreted and exhibit...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Dorner, A J, Wasley, L C, Kaufman, R J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1990
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120699/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7429
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