Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels.
Secretory proteins expressed in Chinese hamster ovary (CHO) cells interact to various degrees with glucose-regulated protein 78 (GRP78), a resident protein of the endoplasmic reticulum. von Willebrand factor (vWF) and wild-type tissue plasminogen activator (tPA) are efficiently secreted and exhibit...
Sparad:
| I publikationen: | Proc Natl Acad Sci U S A |
|---|---|
| Huvudupphov: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
National Academy of Sciences
1990
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120699/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7429 |
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