Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels.

Secretory proteins expressed in Chinese hamster ovary (CHO) cells interact to various degrees with glucose-regulated protein 78 (GRP78), a resident protein of the endoplasmic reticulum. von Willebrand factor (vWF) and wild-type tissue plasminogen activator (tPA) are efficiently secreted and exhibit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Dorner, A J, Wasley, L C, Kaufman, R J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120699/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7429
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