128. Dysregulation of Kynurenine Metabolism is Related to Proinflammatory Cytokines, Prefrontal Cortex Volume, and Attention in Schizophrenia

Background: The kynurenine pathway (KP) of tryptophan (TRP) catabolism is considered to link the immune and neurotransmitter systems. The KP metabolite kynurenic acid (KYNA) shows increases in the brain of patients with schizophrenia. Here, we tested whether changes in brain KP enzyme mRNAs and plas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Schizophr Bull
Prif Awduron: Weickert, Thomas, Kindler, Jochen, Zavitsanou, Katerina, Lim, Chai, Guillemin, Gilles, Galletly, Cherrie, Liu, Dennis, Balzan, Ryan, Boerrigter, Danny, Bruggemann, Jason, O’Donnell, Maryanne, Lenroot, Rhoshel, Weickert, Cynthia Shannon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475646/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.186
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