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128. Dysregulation of Kynurenine Metabolism is Related to Proinflammatory Cytokines, Prefrontal Cortex Volume, and Attention in Schizophrenia
Background: The kynurenine pathway (KP) of tryptophan (TRP) catabolism is considered to link the immune and neurotransmitter systems. The KP metabolite kynurenic acid (KYNA) shows increases in the brain of patients with schizophrenia. Here, we tested whether changes in brain KP enzyme mRNAs and plas...
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| Veröffentlicht in: | Schizophr Bull |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475646/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.186 |
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