128. Dysregulation of Kynurenine Metabolism is Related to Proinflammatory Cytokines, Prefrontal Cortex Volume, and Attention in Schizophrenia

Background: The kynurenine pathway (KP) of tryptophan (TRP) catabolism is considered to link the immune and neurotransmitter systems. The KP metabolite kynurenic acid (KYNA) shows increases in the brain of patients with schizophrenia. Here, we tested whether changes in brain KP enzyme mRNAs and plas...

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書誌詳細
出版年:Schizophr Bull
主要な著者: Weickert, Thomas, Kindler, Jochen, Zavitsanou, Katerina, Lim, Chai, Guillemin, Gilles, Galletly, Cherrie, Liu, Dennis, Balzan, Ryan, Boerrigter, Danny, Bruggemann, Jason, O’Donnell, Maryanne, Lenroot, Rhoshel, Weickert, Cynthia Shannon
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
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Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475646/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.186
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