133. Interplay Between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study

Background: A history of childhood adversity is associated with psychotic disorder, with an increase in risk according to number or severity of exposures. However, it is not known why only some exposed individuals go on to develop psychosis. One possibility is preexisting genetic vulnerability. Rese...

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Détails bibliographiques
Publié dans:Schizophr Bull
Auteurs principaux: Trotta, Antonella, Iyegbe, Conrad, Di Forti, Marta, Sham, Pak C, Campbell, Desmond D, Cherny, Stacey, Mondelli, Valeria, Aitchison, Katherine, Murray, Robin, Vassos, Evangelos, Fisher, Helen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475644/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.191
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